Sleep is a critical component of our overall health, yet many struggle to find restful nights consistently. With a range of factors affecting our sleep quality, from stress to poor bedtime routines, the quest for better sleep is common. Nootropics, often referred to as cognitive enhancers, offer potential solutions beyond traditional sleep aids like melatonin. This article explores a variety of natural nootropics that can help improve sleep quality and duration by targeting different aspects of sleep regulation.
Understanding Sleep and Its Mechanisms
Sleep is governed by complex processes involving multiple sleep stages and the regulation of various neurotransmitters. There are two primary types of sleep: Rapid Eye Movement (REM) and Non-REM (NREM), each playing a vital role in our health. NREM sleep includes stages of light to deep sleep, crucial for physical recovery and brain detoxification. REM sleep, on the other hand, supports cognitive functions such as memory consolidation and emotional regulation.
Neurotransmitters like gamma-aminobutyric acid (GABA), serotonin, and naturally produced melatonin regulate these cycles, signalling the brain when it’s time to sleep or wake. Nootropics can influence these neurotransmitters, offering a biochemical approach to improving sleep quality by enhancing the natural sleep-wake cycle and reducing the time it takes to fall asleep.
Top Nootropics for Sleep
Melatonin
Melatonin is well-known for its role in regulating the sleep-wake cycle. As a supplement, it is especially helpful in correcting sleep schedules disrupted by jet lag or shift work, by re-synchronizing the body’s internal clock.
Magnesium
Magnesium plays a multifaceted role in the body, including the regulation of neurotransmitters that control sleep[1]Arab, A., Rafie, N., Amani, R., & Shirani, F. (2023). The role of magnesium in sleep health: a systematic review of available literature. Biological Trace Element Research, 201(1), 112-128. https://doi.org/10.1007/s12011-022-03162-1. It helps to calm the nervous system and prepare the body for rest, making it easier to fall asleep and stay asleep.
L-theanine
Found predominantly in tea leaves, L-theanine is an amino acid that promotes relaxation without sedation. It aids in decreasing the time it takes to fall asleep by helping the mind transition smoothly into a state of rest[2]Dasdelen, M. F., Er, S., Kaplan, B., Celik, S., Beker, M. C., Orhan, C., Tuzcu, M., Sahin, N., Mamedova, H., Sylla, S., Komorowski, J., Ojalvo, S. P., Sahin, K., & Kilic, E. (2022). A novel theanine complex, Mg-L-theanine improves sleep quality via regulating brain electrochemical activity. Frontiers in Nutrition, 9. https://doi.org/10.3389/fnut.2022.874254.
Product | Company | Quantity | Price | Country | Website |
L-Theanine | iHerb | 120 pills (200mg) | $24.13 | Worldwide, AU | Visit Website >> |
5-HTP
5-Hydroxytryptophan (5-HTP) is a precursor to serotonin, a neurotransmitter that is eventually converted into melatonin. By boosting serotonin levels, 5-HTP can improve both mood and sleep quality[3]Sutanto, C., Heng, C. W., Gan, A. X., Wang, X., Fam, J., & Kim, J. E. (2021). The impact of 5-hydroxytryptophan supplementation on sleep quality of older adults in Singapore: A randomized controlled trial. Current Developments in Nutrition, 5(Suppl 2), 372. https://doi.org/10.1093/cdn/nzab037_082, facilitating a smoother transition to sleep.
5-HTP | iHerb | 120 pills (100 mg) | $16.79 | Worldwide, AU | Visit Website >> |
Ashwagandha
This ancient herb is renowned for its adaptogenic properties, helping to manage stress and anxiety. By reducing cortisol levels and stabilizing the body’s stress response[4]Salve, J., Pate, S., Debnath, K., & Langade, D. (2019). Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults: A double-blind, randomized, placebo-controlled clinical study. Cureus, 11(12). https://doi.org/10.7759/cureus.6466, Ashwagandha can lead to better sleep quality and duration.
Product | Company | Quantity | Price | Country | Website |
Ashwagandha | iHerb | 120 pills (300mg) | $20.24 | Worldwide, AU | Visit Website >> |
Bacopa monnieri
Bacopa monnieri supports the brain’s ability to process information during REM sleep[5]McPhee, G. M., Downey, L. A., Wesnes, K. A., & Stough, C. (2021). The neurocognitive effects of Bacopa monnieri and cognitive training on markers of brain microstructure in healthy older adults. Frontiers in Aging Neuroscience, 13. https://doi.org/10.3389/fnagi.2021.638109, making it not only beneficial for sleep but also for cognitive function. It is also noted for its anti-anxiety effects, which can help ease the transition into sleep.
Product | Company | Quantity | Price | Country | Website |
Bacopa monnieri | iHerb | 1 fl. oz. (30ml) | $15.01 | Worldwide, AU | Visit Website >> |
Phenibut
As a derivative of GABA, Phenibut can cross the blood-brain barrier more effectively than GABA itself. It works by reducing anxiety and stress levels, thereby improving sleep quality[6]Scott, A. J., Webb, T. L., Martyn-St James, M., Rowse, G., & Weich, S. (2021). Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials. Sleep Medicine Reviews, 60. https://doi.org/10.1016/j.smrv.2021.101556 without impacting cognitive performance.
Product | Company | Quantity | Price | Country | Website |
Phenibut HCl Powder | PureRawz | 25g | $23.48 | Worldwide, US, AU | Visit Website >> |
Combining Nootropics for Optimal Sleep
While individual nootropics offer specific benefits, combining them can enhance their effects. However, it is crucial to approach this practice with caution and knowledge. For instance, stacking L-Theanine with 5-HTP can enhance both the quality of sleep and the ease of waking up. Magnesium, when taken with Melatonin, can provide a more restorative sleep cycle[7]Zisapel, N. (2018). New perspectives on the role of melatonin in human sleep, circadian rhythms, and their regulation. British Journal of Pharmacology, 175(16), 3190-3199. https://doi.org/10.1111/bph.14116 by deepening sleep stages.
It’s recommended to start with lower dosages and gradually adjust based on personal tolerance and effectiveness. Always consult with a healthcare provider to tailor the combination to your specific needs and to ensure there are no interactions with other medications.
Lifestyle Considerations and Additional Tips
Adopting nootropics for better sleep should be complemented with good sleep hygiene practices. These lifestyle adjustments not only enhance the effectiveness of nootropics but also ensure that you maintain a natural sleep-wake cycle:
Establish a Regular Sleep Schedule
Stick to a consistent bedtime and wake-up time every day, even on weekends. This regularity helps reinforce your body’s natural circadian rhythm.
Create a Restful Environment
Your bedroom should be conducive to sleep. Consider factors like temperature, noise, and light. Keeping the room cool, quiet, and dark can significantly improve sleep quality.
Limit Screen Time Before Bed
Exposure to blue light from screens can inhibit melatonin production, making it harder to fall asleep. Try to avoid electronic devices for at least an hour before bedtime.
Mind Your Diet
Avoid large meals, caffeine, and alcohol before sleep. These can disrupt sleep or delay sleep onset. Instead, opt for light snacks that are high in tryptophan and magnesium, which can aid the sleep process.
Integrating these practices with nootropic supplementation can lead to substantial improvements in sleep quality and duration, reducing the likelihood of sleep disturbances.
Conclusion
Incorporating nootropics into your nightly routine can offer significant benefits for those struggling with sleep issues. From melatonin to Phenibut, each nootropic has unique properties that can enhance different aspects of sleep. However, it’s crucial to approach their use thoughtfully, considering both the synergistic effects of combining them and the lifestyle factors that influence sleep.
Consultation with a healthcare provider is recommended to tailor nootropic use to your individual needs and to address any underlying health issues. With the right approach, nootropics can be a valuable addition to your arsenal for achieving better, more restorative sleep, ultimately improving your overall health and well-being.
References
↑1 | Arab, A., Rafie, N., Amani, R., & Shirani, F. (2023). The role of magnesium in sleep health: a systematic review of available literature. Biological Trace Element Research, 201(1), 112-128. https://doi.org/10.1007/s12011-022-03162-1 |
---|---|
↑2 | Dasdelen, M. F., Er, S., Kaplan, B., Celik, S., Beker, M. C., Orhan, C., Tuzcu, M., Sahin, N., Mamedova, H., Sylla, S., Komorowski, J., Ojalvo, S. P., Sahin, K., & Kilic, E. (2022). A novel theanine complex, Mg-L-theanine improves sleep quality via regulating brain electrochemical activity. Frontiers in Nutrition, 9. https://doi.org/10.3389/fnut.2022.874254 |
↑3 | Sutanto, C., Heng, C. W., Gan, A. X., Wang, X., Fam, J., & Kim, J. E. (2021). The impact of 5-hydroxytryptophan supplementation on sleep quality of older adults in Singapore: A randomized controlled trial. Current Developments in Nutrition, 5(Suppl 2), 372. https://doi.org/10.1093/cdn/nzab037_082 |
↑4 | Salve, J., Pate, S., Debnath, K., & Langade, D. (2019). Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults: A double-blind, randomized, placebo-controlled clinical study. Cureus, 11(12). https://doi.org/10.7759/cureus.6466 |
↑5 | McPhee, G. M., Downey, L. A., Wesnes, K. A., & Stough, C. (2021). The neurocognitive effects of Bacopa monnieri and cognitive training on markers of brain microstructure in healthy older adults. Frontiers in Aging Neuroscience, 13. https://doi.org/10.3389/fnagi.2021.638109 |
↑6 | Scott, A. J., Webb, T. L., Martyn-St James, M., Rowse, G., & Weich, S. (2021). Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials. Sleep Medicine Reviews, 60. https://doi.org/10.1016/j.smrv.2021.101556 |
↑7 | Zisapel, N. (2018). New perspectives on the role of melatonin in human sleep, circadian rhythms, and their regulation. British Journal of Pharmacology, 175(16), 3190-3199. https://doi.org/10.1111/bph.14116 |
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