Pramiracetam: For Extreme Cognitive Power

<p>Pramiracetam is one of the most  powerful racetams available. If you’re looking for a nootropic that’s  exceptionally strong, it might be just right  for you.</p> <p>Like <a href="http://piracetam.net/piracetam-vs-aniracetam/">Aniracetam</a>, Pramiracetam,  N-(2-(diisopropylamino)ethyl)-2-oxo-l-pyrrolidineacetamide,  is fat soluble. That means  it crosses the blood-brain barrier easily. In fact, Pramiracetam dissolves in  fat more easily than any of the other racetam do. This allows it to be absorbed  very rapidly and could explain why its effect is so stroing.</p> <h2>Effects on Cognition</h2> <p>Pramiracetam was developed by Parke,  Davis and Co., which reported the drug’s nootropic effects in 1978. Since then,  further research has demonstrated its neuroprotective and memory enhancing  effects.</p> <p>Studies in rats and mice have shown  that Pramiracetam <a href="http://www.sciencedirect.com/science/article/pii/S0166432889800518">improves  retention</a>, enhances <a href="http://link.springer.com/article/10.1007%2FBF00174378">spatial learning  ability</a> and helps prevent chemically induced <a href="http://www.sciencedirect.com/science/article/pii/0091305786904089">amnesia</a>.</p> <p>A 1991 study showed that Pramiracetam  improved memory and helped treat other cognitive problems in men with <a href="http://informahealthcare.com/doi/abs/10.3109/02699059109008110">brain injuries</a>.  The improvements persisted a month after the men stopped taking the drug.</p> <p>In 1994, researchers gave male  volunteers scopolamine to induce <a href="http://www.aggjournal.com/article/0167-4943%2894%2900542-7/abstract">amnesia</a>.  When the volunteers were given Pramiracetam, the amnesic effects were partially  reduced.</p> <p>Some studies have suggested that Pramiracetam  could help people with Alzheimer’s disease, but other studies have produced  conflicting results.</p> <p>Pramiracetam users report that it  allows them to think more clearly and focus more easily.</p> <h2>How It Works </h2> <p>Scientists aren’t exactly sure how  Pramiracetam gets its effects. Research shows it <a href="http://www.imaginarymap.com/Piracetam%20and%20Other%20Nootropics.pdf">increases choline uptake</a> in  the cerebral cortex and in the hippocampus, which plays a role in memory formation.  Choline is a precursor to acetylcholine, a neurotransmitter associated with  learning and memory.</p> <p>Pramiracetam has also been shown to  increase blood flow to the brain. It appears to increase <a href="http://www.sciencedirect.com/science/article/pii/S0006295296004637">brain  membrane fluidity</a> in old, but not young rats.</p> <p>Although some users claim that Pramiracetam  helps with social anxiety, it hasn’t been shown to have any effect on <a href="http://onlinelibrary.wiley.com/doi/10.1002/ddr.430030503/abstract">dopamine  or serotonin</a> receptors. If you’re specifically trying to relieve social  anxiety, you’re better off taking Aniracetam, which does affect these  neurotransmitter receptors.</p> <h2>How Take It</h2> <p>Pramiracetam is much stronger than <a href="http://www.piracetam.net/">Piracetam</a>. Research on rats shows that a  dose of Pramiracetam can have 10 to 15 times the effect as the same dose of  Piracetam. </p> <p>Recommended doses of Pramiracetam range  from 75 to 1500 milligrams day. These should be broken up into two or three  doses throughout the day.</p> <p>In fact, Pramiracetam is so powerful  on its own that it’s been recommended that you don’t stack it with any other  nootropic. You can take it with <a href="http://piracetam.net/taking-choline-piracetam/">choline</a> to prevent  headaches.</p> <p>Piracetam in powder form is known to  have an exceptionally bitter taste, to the point of being almost unpalatable. Because  it isn’t water soluble, you can’t mix it with juice. Instead, you can mix it  with something fatty, such as milk. You can buy Piracetam in pill form, but it  will cost more and you won’t be able to make small dosage adjustments.</p>Pramiracetam is one of the most powerful racetams available. If you’re looking for a nootropic that’s  exceptionally strong, it might be just right for you.

Like Aniracetam, Pramiracetam, N-(2-(diisopropylamino)ethyl)-2-oxo-l-pyrrolidineacetamide, is fat soluble. That means it crosses the blood-brain barrier easily. In fact, Pramiracetam dissolves in fat more easily than any of the other racetams do. This allows it to be absorbed very rapidly and could explain why its effect is so strong.

Effects on Cognition

Pramiracetam was developed by Parke, Davis and Co., which reported the drug’s nootropic effects in 1978. Since then, further research has demonstrated its neuroprotective and memory enhancing effects.

Studies in rats and mice have shown that Pramiracetam improves retention, enhances spatial learning ability and helps prevent chemically induced amnesia.

A 1991 study showed that Pramiracetam improved memory and helped treat other cognitive problems in men with brain injuries. The improvements persisted a month after the men stopped taking the drug.

In 1994, researchers gave male volunteers scopolamine to induce amnesia. When the volunteers were given Pramiracetam, the amnesic effects were partially reduced.

Some studies have suggested that Pramiracetam could help people with Alzheimer’s disease, but other studies have produced conflicting results.

Pramiracetam users report that it allows them to think more clearly and focus more easily.

How It Works

Scientists aren’t exactly sure how Pramiracetam gets its effects. Research shows it increases choline uptake in the cerebral cortex and in the hippocampus, which plays a role in memory formation. Choline is a precursor to acetylcholine, a neurotransmitter associated with learning and memory.

Although some users claim that Pramiracetam helps with social anxiety, it hasn’t been shown to have any effect on dopamine or serotonin receptors. If you’re specifically trying to relieve social anxiety, you’re better off taking Aniracetam, which does affect these neurotransmitter receptors.

milkHow Take It

Pramiracetam is much stronger than Piracetam. Research on rats shows that a dose of Pramiracetam can have 10 to 15 times the effect of the same dose of Piracetam.

Recommended doses of Pramiracetam range from 75 to 1500 milligrams day. These should be broken up into two or three doses throughout the day.

In fact, Pramiracetam is so powerful on its own that it’s been recommended that you don’t stack it with any other nootropic. You can take it with choline to prevent headaches.

Pramiracetam in powder form is known to have an exceptionally bitter taste, to the point of being almost unpalatable. Because it isn’t water soluble, you can’t mix it with juice. Instead, you can mix it with something fatty, such as milk. You can buy Pramiracetam in pill form, but it will cost more and you won’t be able to make small dosage adjustments.

Comments

  1. By Paul Brown on

    I bought some Pramiracetam in pill form 300mg. I think it has an effect. Can I take more? Where can I buy it in powder from in Australia?

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